IL1RAP Polyclonal Antibody

Background:
Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.

Research Area: Cancer, Cardiovascular, Immunology

Synonyms:
IL1RAP, C3orf13, IL-1RAcP, IL1R3

Immunogen: Recombinant fusion protein of human IL1RAP (NP_001161402.1).

Swissprot: Q9NPH3
Gene ID: 3556

Calculated MW: 39 kDa/41 kDa/65 kDa/78 kDa
Observed MW: 90 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.