IL1RN Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Research Area: Cancer, Immunology

Synonyms:
DIRA, F630041P17Rik, ICIL 1RA, ICIL-1RA, ICIL1RA, IL-1ra, IL-1ra3, IL-1RN, IL1 inhibitor, IL1F3, IL1RA, IL1RA, IL1RN (IL1F3), IL1RN, Interleukin 1 receptor antagonist, Interleukin-1 receptor antagonist protein, Intracellular IL 1 receptor antagonist type II, Intracellular interleukin 1 receptor antagonist (icIL 1ra), IRAP, MGC10430, MVCD4, Type II interleukin 1 receptor antagonist

Immunogen: Synthetic peptide of human IL1RN

Swissprot: P18510
Gene Accession: NP776214

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.96 mg/mL
Dilution: IHC 1:50-1:100, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.