IL2RB Polyclonal Antibody

Background:
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.

Research Area: Immunology, Signal Transduction, Stem Cells

Synonyms:
CD122, CD122 antigen, High affinity IL 2 receptor beta subunit, High affinity IL 2 receptor subunit beta, High affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2R subunit beta, IL-2RB, IL15RB, IL2 receptor, IL2RB, IL2RB, Interleukin 2 receptor beta, Interleukin-2 receptor subunit beta, P70 75, P70-75, P7075, p75

Immunogen: Recombinant protein of human IL2RB

Swissprot: P14784
Gene Accession: BC025691

Calculated MW: 61 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-20750/sc-1046/sc-671