IL34 polyclonal, anti-human

Background:
Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.

Synonyms: IL-34, C16orf77

Cellular Location: Secreted

Immunogen:
A synthetic peptide of human IL34

Gene Symbol: IL34

Gene ID: 146433

Swiss prot: Q6ZMJ4

Calculated MW: 27kDa

Recommended dilution:
WB 1:200-1000, IHC 1:30-150,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.