IL6R antibody (clone 2G6), anti-human
€435.00
In stock
SKU
AC-AT2522a
Catalog Number: AC-AT2522a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, E
Request Information AC-AT2522a">Request Information
Background:
Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. The protein encoded by this gene is a subunit of the receptor complex for IL6. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Other Names:
Interleukin-6 receptor subunit alpha, IL-6 receptor subunit alpha, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL-6R 1, Membrane glycoprotein 80, gp80, CD126, IL6R
Antigen Type:
Recombinant Protein
Gene Name: IL6R (HGNC:6019)
Gene ID: 3570
NCBI Accession: NP_000556.1;NP_001193795.1;NP_852004.1
Primary Accession: P08887
Other Accession: NM_000565
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. The protein encoded by this gene is a subunit of the receptor complex for IL6. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Other Names:
Interleukin-6 receptor subunit alpha, IL-6 receptor subunit alpha, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL-6R 1, Membrane glycoprotein 80, gp80, CD126, IL6R
Antigen Type:
Recombinant Protein
Gene Name: IL6R (HGNC:6019)
Gene ID: 3570
NCBI Accession: NP_000556.1;NP_001193795.1;NP_852004.1
Primary Accession: P08887
Other Accession: NM_000565
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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