IL6R polyclonal, anti-human

Background:
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.

Synonyms: CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80

Cellular Location: Basolateral cell membrane Secreted Single-pass type I membrane protein

Immunogen:
Recombinant protein of human IL6R

Gene Symbol: IL6R

Gene ID: 3570

Swiss prot: P08887

Calculated MW: 52kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.