ILK (P240) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS3743
Background:
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin linked kinase (ILK), interacts with the cytoplasmic domain of beta 1 Integrin. ILK encodes a predicted 451 amino acid protein, with an apparent molecular weight of 59 kDa. The ILK protein is a serine/threonine protein kinase with 4 ankyrin like repeats. ILK regulates integrin mediated signal transduction.
Alternative Name:
Integrin-linked protein kinase, 59 kDa serine/threonine-protein kinase, ILK-1, ILK-2, p59ILK, ILK, ILK1, ILK2
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: ILK (P240) polyclonal antibody detects endogenous levels of ILK protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 212-258 of Human ILK.
MW: ~ 51 kDa
Swis Prot.: Q13418
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin linked kinase (ILK), interacts with the cytoplasmic domain of beta 1 Integrin. ILK encodes a predicted 451 amino acid protein, with an apparent molecular weight of 59 kDa. The ILK protein is a serine/threonine protein kinase with 4 ankyrin like repeats. ILK regulates integrin mediated signal transduction.
Alternative Name:
Integrin-linked protein kinase, 59 kDa serine/threonine-protein kinase, ILK-1, ILK-2, p59ILK, ILK, ILK1, ILK2
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: ILK (P240) polyclonal antibody detects endogenous levels of ILK protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 212-258 of Human ILK.
MW: ~ 51 kDa
Swis Prot.: Q13418
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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