ILK (Restricted sale due to demands of patent holder) polyclonal, anti-human, mouse

Background:
Receptor-proximal protein kinase regulating integrin- mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.

Other Names:
Integrin-linked protein kinase, 2.7.11.1, 59 kDa serine/threonine-protein kinase, ILK-1, ILK-2, p59ILK, ILK, ILK1, ILK2

Antigen Types:
Synthetic Peptide

Gene Name:
ILK (HGNC:6040)
Gene ID:
3611
Primary Accession: Q13418
Other Accession: NP_004508.1; NP_001014794.1; NP_001014795.1;3611;