ILK1 polyclonal, anti-human, mouse, rat antibody

ILK1 polyclonal, anti-human, mouse, rat antibody

€275.00
In stock
SKU
AC-ABV10308-100
Catalog Number: AC-ABV10308-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC
Datasheet

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Background:
ILKs (Integrin-linked kinases) in combination with integrins and growth factors regulate cell survival, cell cycle, cell-cell adhesion and cell motility. ILK functions as a scaffold bridging the extra-cellular matrix (ECM) and growth factor receptors to the actin cytoskeleton thro µgh interactions with integrin, PINCH (which links ILK to the RTKs via Nck2), CH-ILKBP and affixin. ILK phosphorylates several cellular targets including Akt, GSK-3, myosin light chain 2, as well as affixin. These phosphorylation events are key regulatory steps in modulating the activities of the targets.

Other Names:
p59ILK , ILK-1 , P59 , DKFZp686F1765

Primary Accession: O55222

Other Accession: NP_034692

Gene Name: Ilk

Gene ID: 16202

Concentration (mg/ml): 0.5 mg/ml
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