IMPDH1 Antibody (C-term) Blocking peptide

Background:
The protein encoded by this gene acts as a homotetramer toregulate cell growth. The encoded protein is an enzyme thatcatalyzes the synthesis of xanthine monophosphate (XMP) frominosine-5'-monophosphate (IMP). This is the rate-limiting step inthe de novo synthesis of guanine nucleotides. Defects in this geneare a cause of retinitis pigmentosa type 10 (RP10). Severaltranscript variants encoding different isoforms have been found forthis gene.

Other Names:
Inosine-5'-monophosphate dehydrogenase 1 {ECO:0000255|HAMAP-Rule:MF_03156}, IMP dehydrogenase 1 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPD 1 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPDH 1 {ECO:0000255|HAMAP-Rule:MF_03156}, 111205 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPDH-I, IMPDH1 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPD1

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13549b was selected from the C-term region of IMPDH1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: IMPDH1 {ECO:0000255|HAMAP-Rule:MF_03156}

Gene ID: 3614
Primary Accession: P20839
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.