IMPDH1 Polyclonal Antibody

Background:
The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Neuroscience, Signal transduction

Synonyms:
IMDH1, IMP (inosine monophosphate) dehydrogenase 1, IMP dehydrogenase 1, IMPD 1, IMPD, IMPD1, IMPDH 1, IMPDH I, IMPDH-I, Impdh1, Inosine 5' monophosphate dehydrogenase 1, Inosine monophosphate dehydrogenase 1, Inosine-5''-monophosphate dehydrogenase 1, LCA11, RP10, sWSS2608

Immunogen: Synthetic peptide of human IMPDH1

Swissprot: P20839
Gene Accession: NP_001136045

Calculated MW: 55 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-46149/sc-46146/sc-46147/sc-50510