IMPDH1 Polyclonal Antibody

Background:
The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Neuroscience, Signal Transduction

Synonyms:
IMPDH1, IMPD, IMPD1, IMPDH-I, LCA11, RP10, sWSS2608

Immunogen: Recombinant fusion protein of human IMPDH1 (NP_899066.1).

Swissprot: P20839
Gene ID: 3614

Calculated MW: 52 kDa/54 kDa/55 kDa/60 kDa/63 kDa/64 kDa
Observed MW: 55 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:1000-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.