IMPDH2 antibody (clone 1E12-B6), anti-human
€435.00
In stock
SKU
AC-AT2530a
Catalog Number: AC-AT2530a
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IP, E
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Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IP, E
Request Information AC-AT2530a">Request Information
Background:
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Other Names:
Inosine-5'-monophosphate dehydrogenase 2 {ECO:0000255|HAMAP-Rule:MF_03156}, IMP dehydrogenase 2 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPD 2 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPDH 2 {ECO:0000255|HAMAP-Rule:MF_03156}, 111205 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPDH-II, IMPDH2 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPD2
Antigen Type:
Recombinant Protein
Gene Name: IMPDH2 (HGNC:6053)
Gene ID: 3615
NCBI Accession: NP_000875.2
Primary Accession: P12268
Other Accession: BC012840
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Other Names:
Inosine-5'-monophosphate dehydrogenase 2 {ECO:0000255|HAMAP-Rule:MF_03156}, IMP dehydrogenase 2 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPD 2 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPDH 2 {ECO:0000255|HAMAP-Rule:MF_03156}, 111205 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPDH-II, IMPDH2 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPD2
Antigen Type:
Recombinant Protein
Gene Name: IMPDH2 (HGNC:6053)
Gene ID: 3615
NCBI Accession: NP_000875.2
Primary Accession: P12268
Other Accession: BC012840
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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