IMPDH2 polyclonal, anti-human, mouse, rat

Background:
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.

Alternative Name:
IMP dehydrogenase 2, IMPD 2, IMPDH 2, IMPDH2, IMPD2, IMDH2, IMP (inosine monophosphate) dehydrogenase 2, IMP dehydrogenase 2, IMP oxireductase 2, IMPD 2, IMPD2, IMPDH 2, IMPDH II, IMPDH-II, Impdh2, Inosine 5' monophosphate dehydrogenase 2, Inosine 5' phosphate dehydrogenase 2, Inosine monophosphate dehydrogenase type II, Inosine-5''-monophosphate dehydrogenase 2,

Application Dilution:
WB:1:500-1:2,000
ICC/IF:1:50-1:200
IHC:1:50-1:200
FC:1:10-1:50
IP:1:10-1:50

Specificity: IMPDH2 polyclonal antibody detects endogenous levels of IMPDH2 protein.

Immunogen:
Recombinant protein within C-terminal human IMPDH2.

MW: 56 kDa

Swiss-Prot: P12268(Human) P24547(Mouse) E9PU28(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.