IMPDH2 polyclonal, anti-human, mouse, rat

Background:
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.

Synonyms: IMPD2, IMPDH-II

Cellular Location: Cytoplasm Nucleus

Immunogen:
Recombinant protein of human IMPDH2

Gene Symbol: IMPDH2

Gene ID: 3615

Swiss prot: P12268

Calculated MW: 56kDa

Recommended dilution:
WB 1:500-2000, IHC 1:20-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.