IMPDH2 Polyclonal Antibody

Background:
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
IMPDH2, IMPD2, IMPDH-II

Immunogen: Recombinant fusion protein of human IMPDH2 (NP_000875.2).

Swissprot: P12268
Gene ID: 3615

Calculated MW: 55 kDa
Observed MW: 56 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.