INCA1 polyclonal, anti-human, mouse, rat
€484.00
In stock
SKU
254193
Protein Family: Enzymes
Pathway and Disease: Signaling Molecules and Interaction
Description:
INCA1 was isolated through a yeast triple hybrid approach to identify interaction partners of the cyclin A1-CDK2 heterodimer. INCA1 is evolutionarily conserved and has no homology to any known proteins. Like Cyclin A1, INCA1 is highly expressed in testis with highest levels observed at various points of testis maturation. It has been suggested that the complex of INCA1 and the cyclinA1-CDK2 dimer plays a role in several signaling pathways important for cell cycle control and meiosis. Recent experiments have shown that INCA1 also interacts with the testis protein RSB-66 and this interaction takes place in the cytoplasm.
Alternate Names: INCA1, Inhibitor of CDK1 interacting with cyclin A1, HSD45
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: NP_976248
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human INCA1.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction
Description:
INCA1 was isolated through a yeast triple hybrid approach to identify interaction partners of the cyclin A1-CDK2 heterodimer. INCA1 is evolutionarily conserved and has no homology to any known proteins. Like Cyclin A1, INCA1 is highly expressed in testis with highest levels observed at various points of testis maturation. It has been suggested that the complex of INCA1 and the cyclinA1-CDK2 dimer plays a role in several signaling pathways important for cell cycle control and meiosis. Recent experiments have shown that INCA1 also interacts with the testis protein RSB-66 and this interaction takes place in the cytoplasm.
Alternate Names: INCA1, Inhibitor of CDK1 interacting with cyclin A1, HSD45
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: NP_976248
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human INCA1.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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