INDOL1 polyclonal, anti-human

Quantity: 100 µg

Background:
IDO2(Indoleamine 2,3-dioxygenase 2), also called INDOLEAMINE 2,3-DIOXYGENASE-LIKE 1 or INDOL1, is an enzyme encoded by the INDOL1 gene which metabolizes tryptophan in the kynurenine pathway. By genomic sequence analysis, the INDOL1 gene is mapped on chromosome 8p12 just downstream of the INDO gene. And its exact cytogenetic location is 8p11.21. By database analysis using INDO as probe, followed by RT-PCR of total RNA from various tissues, IDO2 is cloned by human and mouse INDOL1. INDOL1 catabolizes tryptophan as determined by Kyn production, but unlike INDO, is inhibited by D-1-methyl-tryptophan(D-1MT) but not the L-1MT stereoisomer. The Gene Structure of the INDOL1 has 11 exons and spans 74 kb.

Description:
Rabbit IgG polyclonal antibody for Indoleamine 2,3-dioxygenase 2 (IDO2) detection. Tested with WB in Human.

Synonyms:
3-dioxygenase 2 antibody, 3-dioxygenase-like protein 1 antibody, EC 1.13.11. antibody, I23O2_HUMAN antibody, IDO 2 antibody, IDO-2 antibody, Ido2 antibody, INDOL 1 antibody, Indoleamine 2 antibody, Indoleamine 2,3 dioxygenase 2 antibody, Indoleamine 2,3 dioxygenase like 1 protein antibody, Indoleamine 2,3 dioxygenase like protein 1 antibody, Indoleamine pyrrole 2,3 dioxygenase like 1 antibody, Indoleamine pyrrole 2,3 dioxygenase like protein 1 antibody, Indoleamine-pyrrole 2 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human INDOL1(1-20aa MLHFHYYDTSNKIMEPHRPN).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.