ING3 antibody (clone 2C4), anti-human, rat
€435.00
In stock
SKU
AC-AT2534a
Catalog Number: AC-AT2534a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IF, Ehttps://www.abcepta.com/products/pdf_download/AT2534a-ING3-Antibody-monoclonal-M02">Request Information AC-AT2534a">Request Information
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IF, Ehttps://www.abcepta.com/products/pdf_download/AT2534a-ING3-Antibody-monoclonal-M02">Request Information AC-AT2534a">Request Information
Background:
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.
Other Names:
Inhibitor of growth protein 3, p47ING3, ING3
Antigen Type:
Recombinant Protein
Gene Name: ING3
Gene ID: 54556
NCBI Accession: NP_061944.2;NP_938008.1
Primary Accession: Q9NXR8
Other Accession: NM_198267
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.
Other Names:
Inhibitor of growth protein 3, p47ING3, ING3
Antigen Type:
Recombinant Protein
Gene Name: ING3
Gene ID: 54556
NCBI Accession: NP_061944.2;NP_938008.1
Primary Accession: Q9NXR8
Other Accession: NM_198267
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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