ING3 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7888
Background:
ING3 belongs to a family of proteins containing the plant homeodomain (PHD) finger, which includes transcription factors and proteins that regulate chromatin structure. ING3 is a component of the NuA4 histone acetyltransferase (HAT) complex and can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of ING3 has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of the ING3 gene were detected in head and neck cancers.
Alternative Name:
Eaf 4, Eaf4, FLJ20089, ING 2, ING 3, ING2, Inhibitor of growth family member 3, Inhibitor of growth protein 3, MEAF4, p47 ING 3, p47 ING3, p47 regulator protein, p47ING3, p47ING3 protein,
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:200
Specificity: ING3 polyclonal antibody detects endogenous levels of ING3 protein.
Immunogen:
Recombinant full length Human ING3.
MW: ~ 47 kDa
Swis Prot.: Q9NXR8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
ING3 belongs to a family of proteins containing the plant homeodomain (PHD) finger, which includes transcription factors and proteins that regulate chromatin structure. ING3 is a component of the NuA4 histone acetyltransferase (HAT) complex and can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of ING3 has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of the ING3 gene were detected in head and neck cancers.
Alternative Name:
Eaf 4, Eaf4, FLJ20089, ING 2, ING 3, ING2, Inhibitor of growth family member 3, Inhibitor of growth protein 3, MEAF4, p47 ING 3, p47 ING3, p47 regulator protein, p47ING3, p47ING3 protein,
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:200
Specificity: ING3 polyclonal antibody detects endogenous levels of ING3 protein.
Immunogen:
Recombinant full length Human ING3.
MW: ~ 47 kDa
Swis Prot.: Q9NXR8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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