INHBA Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP11126a
Background:
The inhibin beta A subunit joins the alpha subunit to forma pituitary FSH secretion inhibitor. Inhibin has been shown toregulate gonadal stromal cell proliferation negatively and to havetumor-suppressor activity. In addition, serum levels of inhibinhave been shown to reflect the size of granulosa-cell tumors andcan therefore be used as a marker for primary as well as recurrentdisease. Because expression in gonadal and various extragonadaltissues may vary severalfold in a tissue-specific fashion, it isproposed that inhibin may be both a growth/differentiation factorand a hormone. Furthermore, the beta A subunit forms a homodimer,activin A, and also joins with a beta B subunit to form aheterodimer, activin AB, both of which stimulate FSH secretion.Finally, it has been shown that the beta A subunit mRNA isidentical to the erythroid differentiation factor subunit mRNA andthat only one gene for this mRNA exists in the human genome.
Other Names:
Inhibin beta A chain, Activin beta-A chain, Erythroid differentiation protein, EDF, INHBA
Gene Name: INHBA
Gene ID: 3624
Primary Accession: P08476
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The inhibin beta A subunit joins the alpha subunit to forma pituitary FSH secretion inhibitor. Inhibin has been shown toregulate gonadal stromal cell proliferation negatively and to havetumor-suppressor activity. In addition, serum levels of inhibinhave been shown to reflect the size of granulosa-cell tumors andcan therefore be used as a marker for primary as well as recurrentdisease. Because expression in gonadal and various extragonadaltissues may vary severalfold in a tissue-specific fashion, it isproposed that inhibin may be both a growth/differentiation factorand a hormone. Furthermore, the beta A subunit forms a homodimer,activin A, and also joins with a beta B subunit to form aheterodimer, activin AB, both of which stimulate FSH secretion.Finally, it has been shown that the beta A subunit mRNA isidentical to the erythroid differentiation factor subunit mRNA andthat only one gene for this mRNA exists in the human genome.
Other Names:
Inhibin beta A chain, Activin beta-A chain, Erythroid differentiation protein, EDF, INHBA
Gene Name: INHBA
Gene ID: 3624
Primary Accession: P08476
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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