INO80 Polyclonal Antibody

Background:
This gene encodes a subunit of the chromatin remodeling complex, which is classified into subfamilies depending on sequence features apart from the conserved ATPase domain. This protein is the catalytic ATPase subunit of the INO80 chromatin remodeling complex, which is characterized by a DNA-binding domain. This protein is proposed to bind DNA and be recruited by the YY1 transcription factor to activate certain genes. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
DNA helicase INO80, hINO80, homolog of yeast INO80, INO80, INO80 complex subunit A, INO80 homolog, INO80, INO80A, INOC1, KIAA1259, Putative DNA helicase INO80 complex homolog 1

Immunogen: Synthetic peptide of human INO80

Swissprot: Q9ULG1
Gene Accession: NP060023

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 2.46 mg/mL
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.