INS Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP7277b
Background:
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake.
Other Names:
Insulin, Insulin B chain, Insulin A chain, INS
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7277b was selected from the C-term region of human INS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: INS
Gene ID: 3630
Primary Accession: P01308
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake.
Other Names:
Insulin, Insulin B chain, Insulin A chain, INS
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7277b was selected from the C-term region of human INS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: INS
Gene ID: 3630
Primary Accession: P01308
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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