INS monoclonal (Ascites), anti-human
€470.00
In stock
SKU
AC-AM1985a
Catalog Number: AC-AM1985a
Size: 100 µl
Isotype: mouse IgM
Clone Name: 396CT20.4.4
Applications: WB
Datasheet
Request Information
Size: 100 µl
Isotype: mouse IgM
Clone Name: 396CT20.4.4
Applications: WB
Datasheet
Request Information
Background:
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chainand A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Other Names:
Insulin, Insulin B chain, Insulin A chain, INS
Target/Specificity:
This INS antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 35-64 amino acids from human INS.
Antigen Region:
35-64
Antigen Type: Synthetic Peptide
Gene Name: INS
Gene ID: 3630
Primary Accession: P01308
NCBI Accession: NP_000198.1;NP_001172026.1;NP_001172027.1
Other Accession: NP_001172027.1;NP_000198.1;NP_001172026.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chainand A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Other Names:
Insulin, Insulin B chain, Insulin A chain, INS
Target/Specificity:
This INS antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 35-64 amino acids from human INS.
Antigen Region:
35-64
Antigen Type: Synthetic Peptide
Gene Name: INS
Gene ID: 3630
Primary Accession: P01308
NCBI Accession: NP_000198.1;NP_001172026.1;NP_001172027.1
Other Accession: NP_001172027.1;NP_000198.1;NP_001172026.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
| Is Featured? | No |
|---|
Write Your Own Review