INSIG1 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP8940a
Background:
INSIG1 is an insulin-induced protein. This protein encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins.
Other Names:
Insulin-induced gene 1 protein, INSIG-1, INSIG1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8940a was selected from the N-term region of human INSIG1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: INSIG1 {ECO:0000303|PubMed:9268630, ECO:0000312|HGNC:HGNC:6083}
Gene ID: 3638
Primary Accession: O15503
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
INSIG1 is an insulin-induced protein. This protein encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins.
Other Names:
Insulin-induced gene 1 protein, INSIG-1, INSIG1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8940a was selected from the N-term region of human INSIG1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: INSIG1 {ECO:0000303|PubMed:9268630, ECO:0000312|HGNC:HGNC:6083}
Gene ID: 3638
Primary Accession: O15503
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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