INSL3 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Insulin-like 3(INSL3), a member of the insulin-like hormone superfamily, is specifically expressed in Leydig cells of the fetal and postnatal testis and in theca cells of the postnatal ovary. It is synthesized as a 131-amino acid preproprotein, which contains a 24-amino acid signal peptide. The human INSL3 gene is assigned to bands p13.2-p12 of the short arm of chromosome 19 with the similar organization to that of insulin and relaxin. INSL3 induces gubernaculum development in an androgen-independent way, while androgen-mediated regression of the CSL occurs independently from Insl3. Moreover, INSL3 is a ligand for LGR8 and INSL3-LGR8 mutations are believed to be associated with human cryptorchidism.

Description:
Rabbit IgG polyclonal antibody for Insulin-like 3 (INSL3) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
INSL 3 antibody, INSL 3 antibody, INSL3 antibody, INSL3_HUMAN antibody, Insulin like 3 antibody, Insulin-like 3 A chain antibody, Ley IL antibody, Ley-I-L antibody, Leydig insulin like peptide antibody, Leydig insulin-like peptide antibody, Relaxin like factor antibody, Relaxin-like factor antibody, RLF antibody, RLNL antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human INSL3(115-131aa CCLSGCTQQDLLTLCPY), different from the related rat and mouse sequences by three amino acids.A synthetic peptide corresponding to a sequence at the C-terminus of human INSL3(115-131aa CCLSGCTQQDLLTLCPY), different from the related rat and mouse sequences by three amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.