InsP5 2-kinase rabbit polyclonal, anti-human, mouse, rat

Backgroud: The protein encoded by this gene is a kinase that phosphorylates position 2 of inositol-1,3,4,5,6-pentakisphosphate to form inositol-1,2,3,4,5,6-hexakisphosphate (InsP6). InsP6 has a variety of functions, including stimulation of DNA repair, endocytosis, and mRNA export. [provided by RefSeq, Nov 2010],catalytic activity:ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + 1D-myo-inositol hexakisphosphate.,domain:The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.,function:Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, non-homologous end-joining, endocytosis, ion channel regulation. It also protects cells from TNF-alpha-induced apoptosis.,similarity:Belongs to the IPK1 type 2 family.,tissue specificity:Ubiquitously expressed, with high expression in heart, brain, testis and placenta.,

Synonyms: IPPK, C9orf12, Inositol-pentakisphosphate 2-kinase, IPK1 homolog, Inositol-1, 3,4,5,6-pentakisphosphate 2-kinase, Ins(1,3,4,5,6)P5 2-kinase, InsP5 2-kinase

Gene Name: IPPK

Gene ID: 64768

SwissProt ID: Q9H8X2

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.