INSRR polyclonal, anti-human, mouse, rat

Background:
The insulin receptor (IR) is a heterodimeric protein complex that has an intracellular beta subunit and an extracellular alpha subunit, which is disulfide- linked to a transmembrane segment.Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.

Alternative Name:
IRR, INSRR, INSRR, INSRR, Insulin receptor related receptor precursor, Insulin receptor-related protein alpha chain, Insulin receptor-related protein beta chain, insulin receptor-related receptor, IR R, IR related receptor, IR-related receptor, IRR, Sir r, Sirr,

Application Dilution:
WB:1:500
IHC:1:50-1:200

Specificity: INSRR polyclonal antibody detects endogenous levels of INSRR protein.

Immunogen:
Recombinant protein

MW: 80 kDa

Swiss-Prot: P14616(Human) Q9WTL4(Mouse) Q64716(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.