Integrin α1 rabbit polyclonal, anti-human, mouse, rat

Backgroud: integrin subunit alpha 1(ITGA1) Homo sapiens This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq, Jul 2008],domain:The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.,function:Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 1 VWFA domain.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. Alpha-1 associates with beta-1. Interacts with RAB21.,

Synonyms: Integrin alpha-1 (CD49 antigen-like family member A, Laminin and collagen receptor, VLA-1, CD antigen CD49a)

Gene Name: ITGA1

Gene ID: 3672

SwissProt ID: P56199

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.