Interferon γ polyclonal, anti-human, mouse, rat

Background:
Interferon (IFN)-γ is an antiviral and antiparasitic agent produced by CD4+/CD8+ lymphocytes and natural killer cells that undergo activation by antigens, mitogens or alloantigens. IFN-γ production modulates T cell growth and differentiation and inhibits the growth of B cells. Synthesis of IFN-γ is inducible by IL-2, FGF and EGF. The active form of IFN-γ is a homodimer with each subunit containing six helices. The dimeric structure of human IFN-γ is stabilized by non-covalent interactions through the interface of the helices. IFN-γ translated precursor is 166 amino acids, including the 23 amino acid secretory sequence. Multiple forms exist due to variable glycosylation and under non-denaturing conditions due to dimers and tetramers.

Alternative Name:
IFN-gamma, IFNG, IFG, IFI, IFN gamma, IFN, immune, IFN-gamma, IFNG, IFNG, Immune interferon, Interferon gamma,

Application Dilution:
WB:1:500-1:1,000
FC:1:50-1:100
IHC:1:50-1:100

Specificity: Interferon γ polyclonal antibody detects endogenous levels of Interferon γ protein.

Immunogen:
recombinant protein

MW: 19 kDa

Swiss-Prot: P01579(Human) P01580(Mouse) P01581(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.