Interferon gamma polyclonal, anti-rat

Quantity: 100 µg

Background:
Interferon-gamma (IFN-gamma) is an inflammatory cytokine that has been implicated in the development of fibrosis in inflamed tissues. The production of IFN-gamma, which is under genetic control, can influence the development of fibrosis in lung allografts. IFN-gamma is also produced by natural killer (NK) cells and most prominently by CD8 cytotoxic T cells, and is vital for the control of microbial pathogens. Interferon gamma is believed to be crucial for host defence against many infections. Genetically determined variability in IFN-gamma and expression might be important for the development of tuberculosis. IFN-gamma activates human macrophage oxidative metabolism and antimicrobial activity. In addition to having antiviral activity, IFN-gamma has important immunoregulatory functions. IFN-gamma plays an important role in the control of neointima proliferation.

Description:
Rabbit IgG polyclonal antibody for Interferon gamma (IFNG) detection. Tested with WB, ELISA in Rat.

Synonyms:
IFG antibody, IFI antibody, IFN Gamma antibody, IFN Immune antibody, IFN, immune antibody, IFN-gamma antibody, IFNG antibody, IFNG_HUMAN antibody, Immune Interferon antibody, Interferon gamma antibody, Interferon Gamma Precursor antibody, Macrophage Activating Factor antibody, MAF antibody, T Cell Interferon antibody, Type II Interferon antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived rat Interferon gamma recombinant protein (Position: Q23-C156). Rat Interferon gamma shares 38% and 86% amino acid (aa) sequences identity with human and mouse Interferon gamma, respectively.E.coli-derived rat Interferon gamma recombinant protein (Position: Q23-C156). Rat Interferon gamma shares 38% and 86% amino acid (aa) sequences identity with human and mouse Interferon gamma, respectively.

Form: Lyophilized; Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: rat

Applications: WB, ELISA

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.