Interleukin-12 p40 (IL12 p40) polyclonal, anti-human

Quantity: 100 µg

Background:
IL-12, Interleukin 12, heterodimerizes with the IL12 p35 subunit to form IL12 and with the IL23 p19 subunit to form IL23. IL12b p 40 exists as a monomer and as a homodimer. This gene encodes a subunit of Interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The IL-12b gene contains 8 exons, the first and last of which are noncoding. By PCR analysis of DNA from rodent/human cell hybrids containing intact chromosomes or translocation chromosomes, the IL-12b gene is mapped to 5q31-q33.This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.

Description:
Rabbit IgG polyclonal antibody for Interleukin-12 subunit beta (IL12B) detection. Tested with WB in Human.

Synonyms:
40 kD Subunit antibody, CLMF 2 antibody, CLMF antibody, CLMF p40 antibody, CLMF2 antibody, Cytotoxic lymphocyte maturation factor 2 antibody, Cytotoxic lymphocyte maturation factor 2 p40 antibody, Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody, HGNC:5970 antibody, IL 12 subunit p40 antibody, IL 12B antibody, IL-12 subunit p40 antibody, IL-12B antibody, IL12 subunit p40 antibody, IL12B antibody, IL12B_HUMAN antibody, Interleukin 12 beta chain antibody, Interleukin 12 p40 antibody, Interleukin 12 subunit beta antibody, Interleukin 12B antibody, Interleukin-12 subunit beta antibody, Natural killer cell stimulatory factor 2 antibody, NK cell stimulatory factor chain 2 antibody, NKSF 2 antibody, NKSF antibody, NKSF2 antibody, p40 antibody, TcMF antibody, TSF antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human IL12 p40(23-40aa IWELKKDVYVVELDWYPD).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.