Interleukin-13 (IL13) polyclonal, anti-rat

Quantity: 100 µg

Background:
IL-13, Interleukin 13, is a protein that in humans is encoded by the IL-13 gene. IL-13 is a kind of cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, which is an important mediator of allergic inflammation and disease. The IL-13 gene is mapped to 5q23-q31. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. This gene acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.

Description:
Rabbit IgG polyclonal antibody for Interleukin-13 (IL13) detection. Tested with ELISA in Rat.

Synonyms:
Allergic rhinitis antibody, ALRH antibody, BHR1 antibody, Bronchial hyperresponsiveness 1 (bronchial asthma) antibody, IL 13 antibody, IL-13 antibody, Il13 antibody, IL13_HUMAN antibody, Interleukin 13 antibody, Interleukin-13 antibody, MGC116786 antibody, MGC116788 antibody, MGC116789 antibody, NC30 antibody, P600 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E. coli-derived rat IL13 recombinant protein (Position: P22-H131). Rat IL13 shares 62% and 76% amino acid (aa) sequence identity with human and mouse IL13, respectively.E. coli-derived rat IL13 recombinant protein (Position: P22-H131). Rat IL13 shares 62% and 76% amino acid (aa) sequence identity with human and mouse IL13, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: rat

Applications: ELISA

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.