Interleukin-18 (IL18) polyclonal, anti-mouse

Quantity: 100 µg

Background:
Interleukin-18, also known as IL18, is a protein which in humans is encoded by the IL18 gene. IL-18 is a cytokine produced by macrophages and other cells that belongs to the IL-1 superfamily. It is mapped to 11q22.2-q22.3. IL-18 works by binding to the interleukin-18 receptor, and together with IL-12, it induces cell-mediated immunity following infection with microbial products like lipopolysaccharide (LPS). After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-γ (IFN-γ) or type II interferon that plays an important role in activating the macrophages or other cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production in B cells.

Description:
Rabbit IgG polyclonal antibody for Interleukin-18 (IL18) detection. Tested with WB in Mouse.

Synonyms:
Iboctadekin antibody, IFN gamma inducing factor antibody, IFN-gamma-inducing factor antibody, IGIF antibody, IL 1 gamma antibody, IL 18 antibody, IL 1g antibody, IL-1 gamma antibody, IL-18 antibody, IL1 gamma antibody, IL18 antibody, IL18 protein antibody, IL18_HUMAN antibody, IL1F4 antibody, IL1g antibody, IL1gamma antibody, ILIF4 antibody, Interferon gamma inducing factor antibody, Interferon gamma-inducing factor antibody, Interleukin 1 gamma antibody, Interleukin 18 antibody, Interleukin-1 gamma antibody, Interleukin-18 antibody, Interleukin18 antibody, MGC12320 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived mouse IL18 recombinant protein (Position: N36-S192). Mouse IL18 shares 66% and 91% amino acid (aa) sequence identity with human and rat IL18, respectively.E.coli-derived mouse IL18 recombinant protein (Position: N36-S192). Mouse IL18 shares 66% and 91% amino acid (aa) sequence identity with human and rat IL18, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.