Interleukin-3 (IL3) polyclonal, anti-mouse

Quantity: 100 µg

Background:
Interleukin 3, also known as IL-3, is a protein that in humans is encoded by the IL3 gene. Ot is mapped to 5q31.1. IL-3 is an interleukin, a type of biological signal (cytokine) that can improve the body's natural response to disease as part of the immune system. It acts by binding to the interleukin-3 receptor. IL-3 stimulates the differentiation of multipotent hematopoietic stem cells into myeloid progenitor cells or, with the addition of IL-7, into lymphoid progenitor cells. In addition, IL-3 stimulates proliferation of all cells in the myeloid lineage (granulocytes, monocytes, and dendritic cells), in conjunction with other cytokines, e.g., Erythropoietin (EPO), Granulocyte macrophage colony-stimulating factor (GM-CSF), and IL-6. IL-3 is secreted by basophils and activated T cells to support growth and differentiation of T cells from the bone marrow in an immune response.

Description:
Rabbit IgG polyclonal antibody for Interleukin-3 (IL3) detection. Tested with WB in Mouse.

Synonyms:
Colony stimulating factor multiple antibody, Hematopoietic growth factor antibody, IL 3 antibody, IL-3 antibody, IL3 antibody, IL3_HUMAN antibody, Interleukin 3(colony stimulating factor, multiple) antibody, Interleukin 3 antibody, Interleukin-3 antibody, Mast cell growth factor antibody, MCGF antibody, MGC79398 antibody, MGC79399 antibody, Multi CSF antibody, Multilineage colony stimulating factor antibody, Multipotential colony stimulating factor antibody, Multipotential colony-stimulating factor antibody, OTTHUMP00000065963 antibody, P cell stimulating factor antibody, P-cell-stimulating factor antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of mouse IL3(122-140aa, RDLDDFRKKLRFYMVHLND).A synthetic peptide corresponding to a sequence in the middle region of mouse IL3(122-140aa, RDLDDFRKKLRFYMVHLND).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.