Interleukin-4 (IL-4) polyclonal, anti-human

Quantity: 100 µg

Background:
Interleukin-4(IL-4), also knowns as a B-cell stimulatory factor1(BSF1), is an immunomodulatory cytokine, which can inhibit the growth of tumour cells.1 The human cDNA contains a single open reading frame encoding a protein of 153 amino acids, including a putative signal peptide. IL-4 may act as an autocrine growth factor in pancreatic cancer cells and also give rise to the possibility that cancer-derived IL-4 may suppress cancer-directed immunosurveillance in vivo in addition to its growth-promoting effects, thereby facilitating pancreatic tumor growth and metastasis.1 The mouse and human genes and their protein products show structural and functional similarities. The human IL-4 gene, which occurs as a single copy in the haploid genome, is mapped on chromosome 5.2 The standard product used in this kit is recombinant human IL-4, consisting of 130 amino acids with the molecular mass of 14KDa.

Description:
Rabbit IgG polyclonal antibody for Interleukin-4 (IL4) detection. Tested with WB in Human.

Synonyms:
B cell growth factor 1 antibody, B cell IgG differentiation factor antibody, B Cell Stimulatory Factor 1 antibody, B-cell stimulatory factor 1 antibody, BCGF 1 antibody, BCGF1 antibody, Binetrakin antibody, BSF 1 antibody, BSF-1 antibody, BSF1 antibody, HCGF antibody, Hodgkin's Cell Growth Factor antibody, IA Inducing Factor antibody, IGG1 induction factor antibody, IL 4 antibody, IL-4 antibody, IL4 antibody, Il4e12 antibody, Interleukin 4 antibody, Interleukin 4, isoform 1 antibody, Interleukin-4 antibody, Interleukin4 antibody, Lymphocyte stimulatory factor 1 antibody, Macrophage fusion factor antibody, Mast cell growth factor 2 antibody, MCGF2 antibody, MFF antibody, MGC79402 antibody, Pitrakinra antibody, T cell growth factor 2 antibody, TCGF2 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human IL4(72-98aa AATVLRQFYSHHEKDTR).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.