Interleukin-6 (IL6) polyclonal, anti-mouse

Quantity: 100 µg

Background:
Interleukin-6 (IL-6) is a protein that in humans is encoded by the IL6 gene. IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. IL-6 is one of the most important mediators of fever and of the acute phase response. IL-6 is also essential for hybridoma growth and is found in many supplemental cloning media such as briclone. Bowcock et al. (1988) assigned the IL6 gene to chromosome 7p21. By in situ hybridization and Southern blot analysis of mouse-human hybrid cell lines, Sutherland et al. (1988) mapped the IL-6 gene to chromosome 7p15.

Description:
Rabbit IgG polyclonal antibody for Interleukin-6 (IL6) detection. Tested with WB, ELISA in Mouse.

Synonyms:
Interleukin BSF 2 antibody, B cell differentiation factor antibody, B cell stimulatory factor 2 antibody, B-cell stimulatory factor 2 antibody, BSF 2 antibody, BSF-2 antibody, BSF2 antibody, CDF antibody, CTL differentiation factor antibody, Cytotoxic T cell differentiation factor antibody, Hepatocyte stimulating factor antibody, HGF antibody, HPGF antibody, HSF antibody, Hybridoma growth factor antibody, Hybridoma growth factor Interferon beta-2 antibody, Hybridoma plasmacytoma growth factor antibody, IFN-beta-2 antibody, IFNB2 antibody, IL 6 antibody, IL-6 antibody, IL6 antibody, IL6 protein antibody, IL6_HUMAN antibody, Interferon beta 2 antibody, Interferon beta-2 antibody, Interleukin 6 (interferon beta 2) antibody, Interleukin 6 antibody, Interleukin BSF 2 antibody, Interleukin-6 antibody, Interleukin6 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived mouse IL6 recombinant protein (Position: F25-T211). Mouse IL6 shares 40% and 85% amino acid (aa) sequences identity with human and rat IL6, respectively.E.coli-derived mouse IL6 recombinant protein (Position: F25-T211). Mouse IL6 shares 40% and 85% amino acid (aa) sequences identity with human and rat IL6, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse

Applications: WB, ELISA

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.