Intestinal Cell Kinase (Phospho Tyr159) polyclonal antibody, anti-human, mouse, rat

Background:
Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.

Research Area: Cell biology, Epigenetics and nuclear signaling, Signal transduction

Synonyms: Serine/threonine-protein kinase ICK, ICK, KIAA0936, Serine/threonine-protein kinase ICK, Intestinal cell kinase, hICK, Laryngeal cancer kinase 2, LCK2, MAK-related kinase, MRK

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year