INTS10 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS8312
Background:
RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The integrator complex is a multi-protein complex that associates with the C-terminal domain of Pol II and is involved in small nuclear RNA (snRNA) transcription and 3’-end processing. INTS10 (integrator complex subunit 10) is also known as INT10 and is a 710 amino acid protein that is localized to the nucleus. INTS10 is a component of the integrator complex and, as such, is thought to aid in the regulation of 3’-end processing of spliceosomal U1 and U2 snRNAs.
Alternative Name:
Integrator complex subunit 10, Int10, INTS10, C8orf35
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: INTS10 polyclonal antibody detects endogenous levels of INTS10 protein.
Immunogen:
Recombinant full length Human INTS10.
MW: ~ 82 kDa
Swis Prot.: Q9NVR2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The integrator complex is a multi-protein complex that associates with the C-terminal domain of Pol II and is involved in small nuclear RNA (snRNA) transcription and 3’-end processing. INTS10 (integrator complex subunit 10) is also known as INT10 and is a 710 amino acid protein that is localized to the nucleus. INTS10 is a component of the integrator complex and, as such, is thought to aid in the regulation of 3’-end processing of spliceosomal U1 and U2 snRNAs.
Alternative Name:
Integrator complex subunit 10, Int10, INTS10, C8orf35
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: INTS10 polyclonal antibody detects endogenous levels of INTS10 protein.
Immunogen:
Recombinant full length Human INTS10.
MW: ~ 82 kDa
Swis Prot.: Q9NVR2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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