INTS2 polyclonal, anti-human

Background:
Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267).

Alternative Name:
Integrator complex subunit 2, Int2, INTS2, KIAA1287

Application Dilution:
IHC: 1:50~1:200

Specificity: INTS2 polyclonal antibody detects endogenous levels of INTS2 protein.

Immunogen:
Synthetic peptide, corresponding to amino acids 50-100 of Human INTS2.

MW: ~ 134 kDa

Swiss-Prot: Q9H0H0

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.