INTS5 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS8313
Background:
RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The integrator complex is a multi-protein complex that associates with the C-terminal domain of Pol II and is involved in small nuclear RNAs (snRNA) U1 and U2 transcription, specifically in their 3’-box-dependent processing. A component of the integrator complex, INTS5 (integrator complex subunit 5), also known as KIAA1698, is a 1,019 amino acid multi-pass membrane protein localized to the nucleus. The gene encoding INTS5 maps to human chromosome 11q12.3 and mouse chromosome 19 A.
Alternative Name:
Integrator complex subunit 5, Int5, INTS5, KIAA1698
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: INTS5 polyclonal antibody detects endogenous levels of INTS5 protein.
Immunogen:
Recombinant full length Human INTS5.
MW: ~ 108 kDa
Swis Prot.: Q6P9B9
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The integrator complex is a multi-protein complex that associates with the C-terminal domain of Pol II and is involved in small nuclear RNAs (snRNA) U1 and U2 transcription, specifically in their 3’-box-dependent processing. A component of the integrator complex, INTS5 (integrator complex subunit 5), also known as KIAA1698, is a 1,019 amino acid multi-pass membrane protein localized to the nucleus. The gene encoding INTS5 maps to human chromosome 11q12.3 and mouse chromosome 19 A.
Alternative Name:
Integrator complex subunit 5, Int5, INTS5, KIAA1698
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: INTS5 polyclonal antibody detects endogenous levels of INTS5 protein.
Immunogen:
Recombinant full length Human INTS5.
MW: ~ 108 kDa
Swis Prot.: Q6P9B9
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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