INVS polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS71701
Background:
This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Alternative Name:
INV, NPH2, NPHP2,
Application Dilution: WB : 1:500 - 1:2000
Specificity: INVS polyclonal antibody detects endogenous levels of INVS protein.
Immunogen:
Recombinant protein of human INVS
MW: Predicted band size: 118 kDa, Observed band size: Refer to Figures
Swis Prot.: Q9Y283
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Alternative Name:
INV, NPH2, NPHP2,
Application Dilution: WB : 1:500 - 1:2000
Specificity: INVS polyclonal antibody detects endogenous levels of INVS protein.
Immunogen:
Recombinant protein of human INVS
MW: Predicted band size: 118 kDa, Observed band size: Refer to Figures
Swis Prot.: Q9Y283
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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