INVS polyclonal, anti-human, mouse

Background:
This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Synonyms: INV, NPH2, NPHP2

Cellular Location: Cell projection Cytoplasm Membrane Nucleus Peripheral membrane protein cilium cytoskeleton spindle

Immunogen:
Recombinant protein of human INVS

Gene Symbol: INVS

Gene ID: 27130

Swiss prot: Q9Y283

Calculated MW: 118kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.