IP-10 polyclonal, anti-human

Quantity: 100 µg

Background:
C-X-C motif chemokine 10(CXCL10), also known as Interferon gamma-induced protein 10 kDa(IP-10) or small-inducible cytokine B10, is a protein that in humans is encoded by the CXCL10 gene. It is a small cytokine belonging to the CXC chemokine family. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. Luster et al.(1987) reported the isolation of an interferon-inducible gene that encodes a 98-amino acid protein called IP10. The chemokine IFN-gamma-inducible protein 10(IP-10; CXCL10), a CXC chemokine, and its receptor, CXCR3, were found to be overexpressed in lymph node cells of EAMG rats. IP10 inhibits bone marrow colony formation, has antitumor activity in vivo, is a chemoattractant for human monocytes and T cells, and promotes T cell adhesion to endothelial cells.

Description:
Rabbit IgG polyclonal antibody for C-X-C motif chemokine 10 (CXCL10) detection. Tested with WB, IHC-P in Human.

Synonyms:
10 kDa interferon gamma induced protein antibody, 10 kDa interferon gamma-induced protein antibody, C X C motif chemokine 10 antibody, C7 antibody, Chemokine(C X C motif) ligand 10 antibody, Chemokine CXC motif ligand 10 antibody, Crg 2 antibody, CRG2 antibody, CXCL 10 antibody, CXCL10 antibody, CXCL10(1-73) antibody, CXL10_HUMAN antibody, Gamma IP10 antibody, Gamma-IP10 antibody, gIP 10 antibody, GIP10 antibody, IFI 10 antibody, IFI10 antibody, INP 10 antibody, INP10 antibody, Interferon activated gene 10 antibody, Interferon gamma induced cell line antibody, Interferon inducible cytokine IP 10 antibody, Interferon inducible cytokine IP10 antibody, IP 10 antibody, IP-10 antibody, Mob 1 antibody, MOB1 antibody, Protein 10 from interferon(gamma) induced cell line antibody, SCYB 10 antibody, SCYB10 antibody, Small inducible cytokine B10 antibody, Small inducible cytokine B10 precursor antibody, Small inducible cytokine subfamily B(Cys X Cys) member 10 antibody, Small inducible cytokine subfamily B CXC member 10 antibody, Small-inducible cytokine B10 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human IP10(79-98aa SKAIKNLLKAVSKERSKRSP).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.