IP3 Receptor (Phospho Tyr353) Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
This gene encodes an intracellular receptor for inositol 1|4|5-trisphosphate. Upon stimulation by inositol 1|4|5-trisphosphate| this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15| a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.

Research Area: Cancer, Metabolism, Signal transduction, Neuroscience

Synonyms: IP3 Receptor , Phospho Tyr353, Inositol 1, 4, 5-trisphosphate receptor type 1, IP3 receptor isoform 1, IP3R 1, InsP3R1, Type 1 inositol 1, 4, 5-trisphosphate receptor, Type 1 InsP3 receptor

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year