IP3KA rabbit polyclonal, anti-human, mouse, rat

Backgroud: Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.[provided by RefSeq, Apr 2011],catalytic activity:ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate.,enzyme regulation:IP3K is activated by calmodulin.,similarity:Belongs to the inositol phosphokinase (IPK) family.,

Synonyms: ITPKA, Inositol-trisphosphate 3-kinase A, Inositol 1, 4,5-trisphosphate 3-kinase A, IP3 3-kinase A, IP3K A, InsP 3-kinase A

Gene Name: ITPKA

Gene ID: 3706

SwissProt ID: P23677

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.