IQGAP1 Polyclonal Antibody

Background:
This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.

Research Area: Cancer, Signal Transduction

Synonyms:
HUMORFA01, IQ motif containing GTPase activating protein 1, IQGA1, Iqgap1, KIAA0051, p195, Ras GTPase activating like protein 1, Ras GTPase-activating-like protein IQGAP1, RasGAP-like with IQ motifs, SAR1

Immunogen: Synthetic peptide of human IQGAP1

Swissprot: P46940
Gene Accession: NP003861

Calculated MW: 189 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.5 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.