IQGAP1 Polyclonal Antibody

Background:
This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.

Research Area: Cancer, Signal Transduction

Synonyms:
IQGAP1, HUMORFA01, SAR1, p195

Immunogen: Recombinant fusion protein of human IQGAP1 (NP_003861.1).

Swissprot: P46940
Gene ID: 8826

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:200 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.