IRAK-M Polyclonal Antibody

Background:
interleukin 1 receptor associated kinase 3(IRAK3) Homo sapiens This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010],

Alternative Names:
IRAK3, Interleukin-1 receptor-associated kinase 3, IRAK-3, IL-1 receptor-associated kinase M, IRAK-M

Immunogen: The antiserum was produced against synthesized peptide derived from human IRAK3. AA range:491-540

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 68

GeneID: IRAK3

Storage: -20°C/1 year

NOTE: For Research Use Only