IRAK polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Interleukin-1 receptor-associated kinase 1, also called IRAK1, is an enzyme that in humans is encoded by the IRAK1 gene. By radiation hybrid analysis, this gene is mapped to chromosome Xq28. Serine/threonine-protein kinase plays a critical role in initiating innate immune response against foreign pathogens. This gene involved in Toll-like receptor(TLR) and IL-1R signaling pathways. This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor(IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.

Description:
Rabbit IgG polyclonal antibody for Interleukin-1 receptor-associated kinase 1 (IRAK1) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
Il1rak antibody, Interleukin 1 receptor associated kinase 1 antibody, Interleukin-1 receptor-associated kinase 1 antibody, IRAK antibody, IRAK-1 antibody, Irak1 antibody, IRAK1_HUMAN antibody, mPLK antibody, OTTHUMP00000026014 antibody, OTTHUMP00000026015 antibody, OTTHUMP00000026020 antibody, OTTHUMP00000180621 antibody, Pelle antibody, Pelle homolog antibody, Pelle-like protein kinase antibody, Plpk antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human IRAK(18-37aa FLYEVPPWVMCRFYKVMDAL), identical to the related rat and mouse sequences.A synthetic peptide corresponding to a sequence at the N-terminus of human IRAK(18-37aa FLYEVPPWVMCRFYKVMDAL), identical to the related rat and mouse sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.